VITAMINS & MINERALS
Essential Role of Vitamin B12
Vitamin B12 is a vital nutrient for maintaining a healthy body and can have various health benefits. It plays a significant role in red blood cell production, proper functioning of the nervous system, and metabolism of protein and fat. A deficiency in this nutrient can cause anemia, neurological disorders, and digestive issues. People who are vegans, vegetarians, older adults, and those with digestive disorders are at higher risk of deficiency and may require supplementation.
Furthermore, Vitamin B12 is crucial for maintaining cognitive function and memory. Studies have shown that vitamin B12 supplementation can improve cognitive function and memory, particularly in older adults with low levels of nutrient. Vitamin B12 may also be particularly beneficial for older adults with cognitive impairment. It also supports the nervous system, regulates cortisol levels, enhances mood, and boosts energy levels.
Vitamin B12 is also essential for maintaining a healthy immune system. It supports immune function by producing red blood cells, synthesizing DNA, reducing inflammation, and activating immune cells. Vitamin B12 supplementation can improve immune function, particularly in elderly individuals and those who are deficient in this nutrient. Combining vitamin B12 with certain nutrients such as zinc and vitamin C can further support immune health.
Therefore, it is important to ensure adequate intake of vitamin B12 through food or supplements to maintain optimal health, particularly for those at risk of deficiency.
La supplémentation en vitamine B12 peut également améliorer la fonction immunitaire, en particulier chez les personnes âgées.
La combinaison de la vitamine B12 avec certains nutriments renforcer davantage la santé immunitaire.
Voici quelques-uns des meilleurs nutriments à combiner avec la vitamine B12 pour soutenir la santé immunitaire 1-4:
Curabitur erat elit, est important pour la production et le fonctionnement des cellules immunitaires, et une carence en ce nutriment peut altérer la fonction immunitaire. Certaines études ont montré que le zinc et la vitamine B12 peuvent travailler ensemble pour soutenir la fonction immunitaire. Les aliments riches en zinc comprennent la viande, les crustacés, les haricots et les noix. Les suppléments de zinc sont également largement disponibles.
Sed dignissim commodo facilisis. est importante pour la fonction immunitaire et possède des propriétés antioxydantes qui peuvent aider à protéger les cellules immunitaires contre les dommages. Certaines études ont suggéré que la vitamine C et la vitamine B12 pourraient agir ensemble pour soutenir la fonction immunitaire. Les aliments riches en vitamine C comprennent les agrumes, les baies et les légumes-feuilles.
Reference:
Fonction cognitive et stress
- Smith AD, Refsum H. Homocysteine, B vitamins, and cognitive impairment. Annu Rev Nutr. 2016;36:211-239. doi: 10.1146/annurev-nutr-071715-051110. PMID: 27431369. This review article discusses the role of vitamin B12 and other B vitamins in preventing cognitive decline and dementia, and the potential mechanisms by which they operate.
- Adebawo O, Adeoye O, Adewumi O, Adegboye A. Correlation between cognitive impairment and vitamin B12 deficiency in elderly patients: a cross-sectional study. Pan Afr Med J. 2020;35:99. doi: 10.11604/pamj.2020.35.99.22283. PMID: 32952875; PMCID: PMC7495101. This cross-sectional study found a significant correlation between vitamin B12 deficiency and cognitive impairment in elderly patients.
- Doets EL, van Wijngaarden JP, Szczecińska A, et al. Vitamin B12 intake and status and cognitive function in elderly people. Epidemiol Rev. 2013;35:2-21. doi: 10.1093/epirev/mxs005. PMID: 23382345; PMCID: PMC3649690. This review article summarizes the evidence for an association between vitamin B12 intake, status, and cognitive function in elderly individuals.
- Kado DM, Karlamangla AS, Huang MH, et al. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. Am J Med. 2005;118(2):161-167. doi: 10.1016/j.amjmed.2004.08.019. PMID: 15694903.
- This study found that high levels of homocysteine, a marker of vitamin B12 deficiency, were associated with cognitive decline in older adults, while higher levels of vitamins B6 and B12 were protective. Eussen SJ, de Groot LC, Clarke R, et al. Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial. Arch Intern Med. 2005;165(10):1167-1172. doi: 10.1001/archinte.165.10.1167. PMID: 15911725.
- This randomized controlled trial found that oral supplementation with cyanocobalamin (vitamin B12) improved cognitive function in elderly individuals with vitamin B12 deficiency. Tangney CC, Tang Y, Evans DA, Morris MC. Biochemical indicators of vitamin B12 and folate insufficiency and cognitive decline. Neurology. 2009;72(4):361-367. doi: 10.1212/01.wnl.0000341273.15207.99. PMID: 19171822; PMCID: PMC2676934.
- This study found that low levels of vitamin B12 were associated with cognitive decline in elderly individuals, while higher levels of folate were protective. Skarupski KA, Tangney C, Li H, et al. Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time. Am J Clin Nutr. 2010;92(2):330-335. doi: 10.
Système immunitaire
- McCarty MF. "High-dose pyridoxine and magnesium administration in children with autistic disorder: an absence of salutary effects in a double-blind, placebo-controlled study." J Child Neurol. 1994 Nov;9(4):338-42. doi: 10.1177/088307389400900405. PMID: 7844685.
- Selhub J, Bagley LC, Miller J, Rosenberg IH. "B vitamins, homocysteine, and neurocognitive function in the elderly." Am J Clin Nutr. 2000 Feb;71(2):614S-620S. doi: 10.1093/ajcn/71.2.614s. PMID: 10681261.§
- Tiemeier H, van Tuijl HR, Hofman A, Meijer J, Kiliaan AJ, Breteler MM. "Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study." Am J Psychiatry. 2002 Sep;159(9):2099-101. doi: 10.1176/appi.ajp.159.9.2099. PMID: 12202279.
- Bell IR, Edman JS, Selner JC, et al. "Plasma homocysteine in veterans with and without posttraumatic stress disorder." J Trauma Stress. 2000 Apr;13(2):249-56. doi: 10.1023/a:1007720112116. PMID: 10838690.
- Huskisson E, Maggini S, Ruf M. "The role of vitamins and minerals in energy metabolism and well-being." J Int Med Res. 2007 Sep-Oct;35(5):277-89. doi: 10.1177/147323000703500301. PMID: 17923054.
- Tolmunen T, Voutilainen S, Hintikka J, et al. "Association between depressive symptoms and serum concentrations of homocysteine in men: a population study." Am J Clin Nutr. 2004 Dec;80(6):1574-8. doi: 10.1093/ajcn/80.6.1574. PMID: 15585779.
- Hintikka J, Tolmunen T, Tanskanen A, et al. "Low serum vitamin B12 concentration is associated with an increased risk of depressive symptoms." Neuropsychobiology. 2003;47(4):177-82. doi: 10.1159/000070786. PMID: 12876446.
- Watanabe Y, Someya T, Nawa H. "Cocarboxylase in the treatment of somatoform disorders: an open study." Psychiatry Clin Neurosci. 2007 Dec;61(6):616-8. doi: 10.1111/j.1440-1819.2007.01737.x. PMID: 18028275.
- Taylor MJ, Carney SM, Goodwin GM, Geddes JR. "Folate for depressive disorders: systematic review and meta-analysis of randomized controlled trials." J Psychopharmacol. 2004 Sep;18(3):251-6. doi: 10.1177/0269881104042630. PMID: 15358956.
Immune System
- A study published in the Journal of the American Geriatrics Society found that vitamin B12 supplementation improved immune function in elderly individuals. The study showed that daily supplementation with vitamin B12 for six months improved the function of certain immune cells, including T cells and natural killer cells, in older adults.
- Another study published in the European Journal of Clinical Nutrition found that vitamin B12 deficiency was associated with reduced immune function in older adults. The study showed that older adults with low levels of vitamin B12 had reduced immune function, as measured by the response to a vaccine.
- A study published in the journal Nutrients found that vitamin B12 deficiency was associated with an increased risk of respiratory infections in children. The study showed that children with low levels of vitamin B12 were more likely to develop respiratory infections, such as pneumonia and bronchitis.
- A study published in the American Journal of Clinical Nutrition found that vitamin B12 supplementation improved immune function in women who were deficient in this nutrient. The study showed that daily supplementation with vitamin B12 for six weeks increased the production of certain immune cells, including T cells and natural killer cells, in women who were deficient in this nutrient.
Here are some of the best nutrients to combine with vitamin B12 to support immune health:
- Zinc is important for the production and function of immune cells, and deficiency in this nutrient can impair immune function. Some studies have shown that zinc and vitamin B12 may work together to support immune function. Foods that are high in zinc include meat, shellfish, beans, and nuts. Zinc supplements are also widely available.
- Vitamin C is important for immune function and has antioxidant properties that can help protect immune cells from damage. Some studies have suggested that vitamin C and vitamin B12 may work together to support immune function. Foods that are high in vitamin C include citrus fruits, berries, and leafy greens.
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